Your Options
There are more options than most people realise — from prescription injections to lifestyle changes to over-the-counter supplements. Here's how they all fit together.
Most people start with one approach and adjust from there. There's no wrong place to begin.
Quick read · 2 min
Want to see everything side by side? Compare all options →
Prescription Medications
FDA-approved drugs including GLP-1 injections and oral pills. Highest weight loss of any category in clinical trials — requires a doctor.
Up to 20.9% average weight loss in trials · $149–$1,350/month · 6 approved drugs →
Future Treatments
5 drugs in late-stage trials — not yet approved. Includes triple agonists and new oral options.
Supplements
20 OTC products reviewed honestly. Evidence ranges from strong (orlistat) to no human trial data.
Modest evidence — we review 20 products honestly
Diet Approaches
Caloric deficit, high protein, low-carb, intermittent fasting. What each approach involves and what trials show.
The foundation — where most people start
Exercise
Fat loss, metabolic health, and muscle preservation. What aerobic exercise, resistance training, and HIIT each do.
Best for overall health and muscle preservation
Body After Weight Loss
Body contouring and skin tightening procedures — for body shaping after significant weight loss.
Cosmetic procedures for after you've lost weight
Based on clinical trials · No rankings · Every claim linked to source
Next step most people take
Last reviewed: March 2026