Independent · Evidence-backed
Every weight-loss treatment, explained in plain English.
What each one does, what the trials found and what it costs — every claim linked to its source.
Start with a treatment
- GLP-1 medicinesZepbound · Wegovy · Saxenda · Foundayo
- Older medicinesQsymia · Contrave · Xenical · Phentermine
- Devices & proceduresPlenity · Gastric Balloon · Endoscopic Sleeve Gastroplasty
- SurgerySleeve Gastrectomy · Gastric Bypass
- SupplementsWhat the evidence shows
- Compare side by sideBuild your own table
Or start with a question
- How much weight do people lose?What the trials measured, and over how long.
- What does it cost?List prices, savings programmes and the gap between them.
- What are the side effects?Which effects are common and which are rare, treatment by treatment.
- Pills or injections?How the two forms differ in practice.
- What happens when you stop?What the studies followed after treatment ended.
- Am I eligible?The criteria prescribers work from.
See the whole picture
Every obesity treatment, on one map.
Medicines old and new, swallowed devices, endoscopic procedures and surgery — what each one achieved in the study behind it.
Average weight loss as a percentage of starting body weight for a sample of treatments, ordered from least to most invasive. Phentermine (Adipex-P, Lomaira), Older prescription drugs, 7.5%. Zepbound & Mounjaro, Approved weight-management drugs, 20.9%. Wegovy pill (oral semaglutide 25mg), Approved weight-management drugs, 16.6%. Plenity (Gelesis100), Swallowed device, 6.4%. Intragastric Balloon (Orbera, Spatz3), Endoscopic procedures, 15%. Gastric Bypass (Roux-en-Y), Bariatric surgery, 29.8%. These figures come from different kinds of studies in different groups of people and are not a head-to-head comparison.
Health-record cohort, 13,972 people, 24 months — not a trial
Phase 3, 64 weeks, vs placebo
Two randomised trials vs lifestyle, 6–8 months, 543 people
Observational, 44,025 patients, 1 year — not a trial
These numbers come from different kinds of studies in different groups of people, so they are shown to get your bearings — not as a head-to-head ranking. Individual results vary.
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Built with agentic AI tools and not a substitute for medical advice