Am I Eligible?

Most weight loss drugs require a BMI of 30 or higher, or 27+ with qualifying health conditions. A doctor makes the final decision.

Quick read · 4 min

In simple terms:
  • Most obesity drugs are prescribed if your BMI is 30 or higher
  • If your BMI is 27–29.9 AND you have conditions like diabetes or high blood pressure, you may also qualify
  • A doctor decides — not a website. This page helps you understand the general criteria.
  • BMI isn't perfect — it doesn't account for muscle mass or body type

Based on clinical trials · No rankings · Every claim linked to source

Last reviewed: March 2026

Check your BMI

Enter your height and weight to see your BMI and whether you would likely meet the standard criteria. This is a guide only — a doctor makes the final decision.

BMI Calculator

Standard FDA eligibility criteria

BMI ≥ 30

Classified as obesity. Eligible for FDA-approved weight loss medications regardless of whether other health conditions are present.

— OR —
BMI ≥ 27 with at least one qualifying health condition

Classified as overweight with a weight-related health condition (like type 2 diabetes, high blood pressure, or sleep apnoea). Qualifying conditions include:

  • Type 2 diabetes
  • High blood pressure (hypertension)
  • High cholesterol (dyslipidaemia)
  • Obstructive sleep apnoea
  • Cardiovascular disease

Source: FDA approved indications + WHO GLP-1 guideline 2024 [1]

Reasons your doctor might say no

These conditions may prevent the use of certain or all weight loss medications. Your doctor will assess these individually.

Medullary thyroid carcinoma (MTC)
Affects: GLP-1 class drugs (all)

Personal or family history of this rare thyroid cancer. FDA black box warning — GLP-1 receptors are found in thyroid cells. Animal studies showed tumour risk, though human risk is not established.

MEN 2 syndrome
Affects: GLP-1 class drugs (all)

Multiple Endocrine Neoplasia type 2 — a rare inherited condition involving a genetic tendency to develop thyroid and other endocrine tumours.

Pregnancy
Affects: Phentermine/topiramate (black box) and GLP-1s (not studied)

Phentermine/topiramate causes cleft palate and other birth defects — absolutely cannot be used. GLP-1s are not approved for use in pregnancy.

Active opioid use
Affects: Naltrexone/bupropion (Contrave)

Naltrexone blocks opioid receptors — cannot be used if you are taking opioids, as it will cause immediate withdrawal.

History of seizures
Affects: Naltrexone/bupropion

Bupropion lowers the seizure threshold — cannot be used in people with a history of seizures.

Glaucoma or hyperthyroidism
Affects: Phentermine/topiramate

Phentermine is a stimulant — not suitable in narrow-angle glaucoma or overactive thyroid (hyperthyroidism).

BMI isn't perfect

BMI is used because it is standardised and easy to measure — not because it perfectly predicts individual health risk.

  • Does not distinguish fat from muscle — a very muscular person may exceed the threshold without significant body fat.
  • Some Asian populations have metabolic risk at lower BMI thresholds — some guidelines use ≥25 or ≥27 with health conditions.
  • Does not capture where fat is stored — belly fat carries higher health risk than fat under the skin.

Who makes the decision?

A prescribing doctor or obesity medicine specialist. The criteria above are the general FDA-approved thresholds — individual decisions may involve additional factors including overall health, other medications, preference, and cost.

Medical disclaimer: This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any treatment.

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