What is obesity?Global prevalence, how BMI is used and its limitations, and what it means to be clinically obese.BasicsHealth consequencesHow obesity increases risk of type 2 diabetes, heart disease, cancer, sleep apnoea, and other conditions.MedicalWhy weight loss is hard to sustainThe biology of hunger hormones, leptin resistance, and why the body actively defends its set point weight.BiologyHow treatments workPlain English explanations of GLP-1, dual agonists, triple agonists, amylin pathway, and oral vs injectable delivery.MechanismsMyths vs factsCommon weight loss claims checked against evidence — from berberine to spot reduction to "just eat less."EvidenceBMI vs waist-to-height ratioBMI is everywhere, but where you carry fat may matter more. What the research shows, and a calculator to check both.Measurement
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Why this matters for treatment
Obesity is now understood as a chronic disease driven by hormonal, genetic, and environmental factors. The treatments reviewed on this site — GLP-1 drugs, dual agonists, surgery — work because they directly address these biological mechanisms, not just calorie balance.
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Medical disclaimer: This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any treatment. Prices shown are United States self-pay or list prices and vary by insurance and country.