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Saxenda

How to take Saxenda

A once-daily pen injection — the practical guide

Quick read · 5 min

Last reviewed: September 2026Every claim linked to source

Saxenda (liraglutide) is a once-daily injection you give yourself under the skin of the abdomen, thigh, or upper arm. The FDA label says you can inject at any time of day, with or without food, and that no dose adjustment is needed if you change the injection site or the timing. The pen dials a dose of 0.6, 1.2, 1.8, 2.4 or 3 mg.


The injection, step by step

Most people master this in 2–3 tries.

1
Wash your hands and check the pen

Wash with soap and water. Check the name and coloured label so you know you have Saxenda, pull off the pen cap, and look through the window: the liquid should be clear and colourless. If it looks cloudy, the Instructions for Use say not to use the pen.

2
Attach a new needle

Tear the paper tab off a new needle, push it straight onto the pen and turn until tight. Pull off the outer cap and keep it; pull off the inner cap and throw it away. The label says to use a new needle for every injection — reusing one risks contamination, infection, leakage and a blocked needle.

3
Check the flow — new pens only

Before your first injection from each new pen, turn the dose selector to the flow check symbol, hold the pen with the needle pointing up, and press the dose button until the counter shows 0. A drop should appear at the tip. If your pen is already in use, skip this step.

4
Select your dose

Turn the dose selector until the counter shows your dose — 0.6, 1.2, 1.8, 2.4 or 3 mg. The Instructions for Use say to read the dose counter and pointer, not to count the clicks and not to use the pen scale.

5
Inject

Wipe the site with an alcohol swab and let it dry. Insert the needle the way your prescriber showed you, then press and hold the dose button until the counter shows 0. Do not cover the dose counter with your fingers — that can stop the injection.

6
Count slowly to 6, then remove

Keep the needle in your skin for a slow count of 6 after the counter reaches 0. Take it out earlier and you may see a stream of Saxenda at the needle tip, which means the full dose was not delivered. If blood appears, press lightly with cotton wool or gauze — do not rub.

7
Take the needle off and cap the pen

Carefully remove the needle without putting the caps back on, and put it straight into a sharps container. Put the pen cap on to protect Saxenda from light, and store the pen with no needle attached.

Three safe injection sites
  • Belly (abdomen) — at least 2 inches from your belly button
  • Front or outer thigh
  • Back of the upper arm

Rotate sites week to week so the same spot doesn't get sore or thickened.

Do this
  • Use a new needle for every injection
  • Check the flow before the first injection from each new pen
  • Rotate your injection site with each injection
  • Count slowly to 6 before pulling the needle out
  • Store the pen with the cap on and no needle attached
  • Carry a spare pen and needles in case of loss or damage
Don't do this
  • Use the pen if the liquid looks cloudy
  • Count the clicks to set your dose — read the dose counter instead
  • Touch the dose counter while injecting — it can stop the dose
  • Put the inner needle cap back on the needle
  • Share your pen with anyone, even with a new needle
  • Draw Saxenda out of the pen with a syringe

Storage

Fridge before you start, then room temperature is fine.

Before first use
Fridge, 36–46°F (2–8°C)
In use
30 days at 59–86°F or in the fridge
Never
Freeze — do not use if it has frozen

If you miss a dose

Simple rules — no double-dosing.

1
You missed a daily dose
Take your next daily dose as usual on the following day.
2
Three days or more without a dose
Call your prescriber. The label restarts Saxenda at 0.6 mg daily and repeats the weekly escalation schedule.
3
Never
Take an extra dose, or increase the next dose, to make up for a missed one.

Common questions

Written and maintained by one person · Built with agentic AI tools · Every number checked against the cited trial · Not medical advice

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Medical disclaimer: This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any treatment.