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Select what matters to you — the list filters to show matching options. This is not a recommendation.

Quick read · 2 min

Zepbound (tirzepatide)
Prescription injection
Up to 20.9%

Trade-off: Requires a prescription · Weekly injection · ~$1,086/month list price

Wegovy injection (semaglutide)
Prescription injection
Up to 14.9%

Trade-off: Requires a prescription · Weekly injection · ~$1,350/month list price

Oral Wegovy (semaglutide pill)
Prescription pill · ~$149/mo
Up to 16.6%

Trade-off: Requires a prescription · Daily pill · 30-min fasting window before each dose

Qsymia (phentermine/topiramate)
Prescription pill · ~$30–80/mo
Up to 9.8%

Trade-off: Requires a prescription · Not suitable during pregnancy · Some cognitive side effects at higher doses

Contrave (naltrexone/bupropion)
Prescription pill · ~$60–150/mo
Up to 9.3%

Trade-off: Requires a prescription · Cannot be taken with opioids · Not suitable with seizure history

Alli (orlistat)
OTC · ~$40–60/mo
Up to 8.5%

Trade-off: Requires a low-fat diet to avoid digestive side effects · More modest weight loss than prescription options

Berberine
Supplement · ~$20–40/mo
~2–3 kg

Trade-off: Evidence is moderate — small trials only · Weight loss is modest (~2–3 kg)

Diet (caloric deficit)
Lifestyle · Free
5–10% typical

Trade-off: Requires sustained consistency · Results depend heavily on adherence over months

This is a filter, not a recommendation. Always speak with a doctor before starting any treatment.

Built with agentic AI tools and not a substitute for medical advice

Last reviewed:

Medical disclaimer: This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any treatment.

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